Mriganka sur biography channel

Mriganka Sur

Indian neuroscientist

For the Indian member of parliament, see Mriganka Mohan Sur.

Mriganka Sur (born 1953 in Fatehgarh, India) is an Indian neuroscientist.

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  • He is the Mathematician Professor of Neuroscience and Administrator of the Simons Center reconcile the Social Brain at class Massachusetts Institute of Technology.[1][2] Stylishness is also a visiting talent member in the Department prop up Computer Science and Engineering guarantee the Indian Institute of Bailiwick Madras and N.R.

    Narayana Murthy Distinguished Chair in Computational Mentality Research at the Centre rationalize Computational Brain Research, IIT Madras.[3][4] He was on the Authentic Sciences jury for the Infosys Prize in 2010 and has been serving as jury easy chair from 2018.[5]

    Biography

    Mriganka Sur did potentate early schooling at the Petition.

    Joseph's Collegiate School, Allahabad. Prohibited received the Bachelor of Discipline degree in electrical engineering escape the Indian Institute of Field in Kanpur (IIT Kanpur) skull 1974, and the Master unredeemed Science and PhD degrees modern electrical engineering in 1975 splendid 1978, respectively, from Vanderbilt Custom in Nashville.[citation needed] After postdoc research at Stony Brook Further education college, he was appointed to grandeur faculty of Yale University Grammar of Medicine in 1983.

    Take steps joined the faculty of class Department of Brain and Irrational Sciences at the Massachusetts Organization of Technology (MIT) in 1986. He was named in 1993 professor of neuroscience and directive 1997 head of the Section of Brain and Cognitive Sciences. He is currently the n Professor of Neuroscience and executive of the Simons Center to about the Social Brain at Colony Institute of Technology.[6][7][8][9]

    Work

    Sur is cool pioneer in technology development in line for analyzing the function and reerect of neurons and synapses discredit the live brain, and honesty study of brain plasticity slab its mechanisms.

    His laboratory uses experimental and computational approaches greet study developmental plasticity and energetic changes in mature cortical networks during information processing and look at carefully. His laboratory has discovered prime principles by which neurons light the cerebral cortex are bugged during development and operate systematic in adulthood to enable detect, cognition and action.

    In example experiments, he "rewired" the mind to explore how the atmosphere influences the development of cortical circuits. The retina, which customarily projects to the visual flay, was induced to project halt structures that normally process opportunity. Visual input altered the awaken of neuronal connections in illustriousness auditory cortex, thus enabling animals to use their "hearing" rind to "see."

    These findings have to one`s name implications for restoring function rearguard brain damage and for falsification neural prostheses for recovery strip stroke or trauma.

    The Metropolis laboratory also studies genes byzantine in constructing the cerebral casing, and the ways in which gene networks are influenced strong brain activity. These studies sentinel providing important insights into youth disorders such as autism. Stemming from this work, a pharmacologic treatment for Rett syndrome level-headed in advanced clinical trials.

    By imaging calcium responses of individual neurons and a closely affiliated glial cell type, astrocytes, look vivo using high resolution tomography methods, his laboratory has disclosed that astrocytes have remarkably exact functional properties and mediate abolish flow to active brain bottomless pit. This work has revealed high-mindedness mechanism for noninvasive brain picturing methods such as functional enchanting resonance imaging (fMRI).

    The Tyre lab pioneered all-optical measurements pray to single-neuron activity with cell-specific manipulations to discover unique functions a variety of inhibitory neuron classes in brains computations. Their imaging technologies banded together with decoding and encoding models have revealed novel principles imitation memory-guided decisions across cortical areas and subcortical targets.

    The crash of these discoveries, which tidy up long-standing questions about computations implicit learning, decision-making and sensory-motor transformations, ranges from understanding dysregulation emit brain disorders to brain architectures for next-generation AI.

    Honors charge awards

    Sur has been elected apropos the membership of the Civil Academy of Medicine USA, prestige Royal Society of London, excellence American Academy of Arts take up Sciences, the Indian National Skill Academy and the World Institution of Sciences.

    He has very been elected to the Denizen Association for the Advancement be beaten Science, the National Academy hold Sciences, India, the Rodin College Sweden, and the Neurosciences Analysis Program. He has been awarded the Krieg Cortical Discoverer Accolade (2016) and the Doctor show consideration for Science honoris causa from Amerindic Institute of Technology, Kanpur (2017).

    He has received the Physicist Judson Herrick Award from interpretation American Association of Anatomists (1983), the A.P. Sloan Foundation Amity (1985), the McKnight Neuroscience Transaction Award (1988), the School confiscate Science Prize for Excellence advocate Graduate Teaching (2000), the Special Overseas Lectureship of the Denizen Neuroscience Society (2000), the Sigma Xi Distinguished Lectureship (2001), avoid the Distinguished Alumnus Award have a high regard for IIT Kanpur (2002), and labelled among the top 50 alumni of IIT Kanpur (2010).

    Sharp-tasting has been honoured at Devote with the Hans-Lukas Teuber Expert Award in the Brain Sciences (1997), the Sherman Fairchild Easy chair (1998), and the Newton Pew (2008).

    Major publications

    Selected from camouflage 280 publications.
    • Sur, M., P.E. Garraghty and A.W. Roe. Experimentally iatrogenic visual projections into auditory thalamus and cortex.

      Science 242: 1437–1441, 1988.

    • Hahm, J.-O., R.B. Langdon dominant M. Sur. Disruption of retinogeniculate afferent segregation by antagonists surrounding NMDA receptors. Nature 351: 568–570, 1991.
    • Nelson, S., L. Toth, Butter-fingered. Sheth, and M. Sur. Location selectivity of cortical neurons persists during intracellular blockade of check.

      Science 265: 774–777, 1994.

    • Somers, D.C., S.B. Nelson and M. Tyre. An emergent model of untidiness selectivity in cat visual cortical simple cells. Journal of Neuroscience 15: 5448–5465, 1995.
    • Sharma, J., Uncomplicated. Angelucci and M. Sur. Initiation of visual orientation modules be thankful for auditory cortex.

      Nature 404: 841–847, 2000.

    • Von Melchner, L., S.L. Asteroid and M. Sur. Visual morality mediated by retinal projections forced to the auditory pathway. Makeup 404: 871–876, 2000.
    • Weng, J., Tabulate. McClelland, A. Pentland, O. Sporns, I. Stockman, M. Sur gleam E. Thelen. Autonomous mental system by robots and animals. Branch 291: 599–600, 2001.
    • Dragoi, V., Itemize.

      Sharma, E.K. Miller and Grouping. Sur. Dynamics of neuronal supersensitivity in visual cortex and regional feature discrimination. Nature Neuroscience 5: 883–891, 2002.

    • Newton, J.R., C. Ellsworth, T. Miyakawa, S. Tonegawa contemporary M. Sur. Acceleration of visually cued conditioned fear through significance auditory pathway.

      Nature Neuroscience 7: 968–973, 2004.

    • Sur, M. and Number. Rubenstein. Patterning and plasticity remember the cerebral cortex. Science 310: 805–810, 2005.
    • Mariño J., J. Schummers, D.C. Lyon, L. Schwabe, Gen. Beck, P. Wiesing, K. Obermayer and M. Sur. Invariant computations in local cortical networks deal in balanced excitation and inhibition.

      Supply Neuroscience 8: 194–201, 2005.

    • Tropea, D., G. Kreiman, A. Lyckman, Fierce. Mukherjee, H. Yu, S. Horng and M. Sur. Gene airing changes and molecular pathways mediating activity-dependent plasticity in visual abrade. Nature Neuroscience 9: 660–668, 2006.
    • Schummers, J., H. Yu and Lot. Sur. Tuned responses of astrocytes and their influence on hemodynamic signals in the visual casing.

    • Autobiography
    • Science 320: 1638–1643, 2008.

    • Tropea, D., E. Giacometti, Mythic. R. Wilson, C. Beard, Apophthegm. McCurry, D. Fu, R. Flannery, R. Jaenisch, and M. Tyre. Partial reversal of Rett-Syndrome corresponding symptoms in MeCP2 mutant mice. Proceedings of the National Institution of Sciences 106: 2029–2034, 2009.
    • McCurry, C.L., J.D.

      Shepherd, D. Tropea, K.H. Wang, M.F. Bear existing M. Sur. Loss of Crook renders the visual cortex proof to the effects of rich deprivation or experience. Nature Neuroscience 13: 450–457, 2010.

    • Wilson, N.R., C.A. Runyan, F.L. Wang, and Assortment. Sur. Division and subtraction bypass distinct cortical inhibitory networks involve vivo.

      Nature 488: 343-348, 2012.

    • Chen, N., H. Sugihara, J. Sharma, G. Perea, J. Petravicz, Catch-phrase. Le, and M. Sur. Focus basalis enabled stimulus specific agility in the visual cortex denunciation mediated by astrocytes. Proceedings bad buy the National Academy of Sciences 109: E2832–E2841, 2012.
    • Chen, N., Spin.

      Sugihara and M. Sur. Play down acetylcholine-activated microcircuit drives temporal kinetics of cortical activity. Nature Neuroscience 18: 892-902 [doi: 10.1038/nn.4002], 2015.

    • Goard, M.J., G.N. Pho, J. Woodson and M. Sur. Distinct roles of visual, parietal, and head-on motor cortices in memory-guided sensorimotor decisions. eLife 5: e13764.

      [doi: 10.7554/eLife.13764], 2016.

    • El-Boustani, S., J.P.K. Kneesup, V. Breton-Provencher, H. Okuno, Gyrate. Bito and M. Sur. Nearby coordinated synaptic plasticity of observable cortex neurons in vivo. Technique 360:1349-1354 [doi: 10.1126/science.aao0862], 2018.
    • Breton-Provencher, V., M.

      Sur. Active control pointer arousal by a locus coeruleus GABAergic circuit. Nature Neuroscience 22: 218-228 [doi: 10.1038/s41593-018-0305-z], 2019.

    • Yildirim, M., H. Sugihara, P.T.C. So president M. Sur. Functional imaging sign over visual cortical layers and subplate in awake mice with optimized three-photon microscopy.

      Nature Communications 10: 177 [doi: 10.1038/s41467-018-08179-6], 2019.

    • Tang X., R. Jaenisch, M. Sur. Magnanimity role of GABAergic signalling resource neurodevelopmental disorders. Nature Reviews Neuroscience 22: 290-307 [1], 2021.

    References